Theranostics: Fusion of Therapeutics and Diagnostics

Bioapplications of Cell-SELEX-Generated Aptamers in Cancer Diagnostics, Therapeutics, Theranostics and Biomarker Discovery: A Comprehensive Review

Currently, functional single-stranded oligonucleotide probes, termed aptamers, generated by an iterative technology, Systematic Evolution of Ligands by Exponential Enrichment (SELEX), are utilized to selectively target molecules or cells with high affinity. Aptamers hold considerable promise as multifunctional molecules or conjugates for challenging nanotechnologies or bioapplications now and i...

Multifunctional magnetoplasmonic nanoparticle assemblies for cancer therapy and diagnostics (theranostics).

In this work, we describe the preparation and biomedical functionalities of complex nanoparticle assemblies with magnetoplasmonic properties suitable for simultaneous cancer therapy and diagnostics (theranostics). Most commonly magnetoplasmonic nanostructures are made by careful adaptation of metal reduction protocols which is both tedious and restrictive. Here we apply the strategy of nanoscal...

Supramolecular Nanoparticles for Molecular Diagnostics and Therapeutics

Gold Nanoparticles in Molecular Diagnostics and Therapeutics

Multifunctional nanoparticles, which incorporate diagnostic (quantum dots, magnetic, metallic, polymeric and silica nanoparticles) and/or therapeutic (magnetic and metallic nanoparticles) properties, are in the process of development. They have been used in vivo to protect the drug entity in the systemic circulation, restrict access of the drug to the chosen sites and to deliver the drug at a c...

Molecular diagnostics and therapeutics for ectopic pregnancy.

Ectopic pregnancies are a serious gynaecological emergency that can be fatal. As such, prompt diagnosis and safe timely treatment is essential. Here, we review the literature on the development of molecularly targeted diagnostics and therapeutics for ectopic pregnancy. A blood-based biomarker that accurately identifies an ectopic pregnancy could be used to offer early diagnostic certainty in ca...